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Showing 1–3 of 3 results
Advanced filters: Author: Abdolhossein Zare Clear advanced filters

  • HnRNP R regulates the axonal transcriptome. Here the authors show that hnRNP R is a component of translation initiation complexes and interacts with O-linked β-N-acetylglucosamine (O-GlcNAc) transferase (Ogt), promoting O-GlcNAcylation of eIF4G.

    • Abdolhossein Zare
    • Saeede Salehi
    • Michael Sendtner
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-20

  • Unconventional protein secretion emerges as an important mechanism in aggregate-prone protein removal. Here, the authors demonstrate that Plekhg5 mediates the unconventional secretion of Sod1 by presynaptic secretory autophagy.

    • Amy-Jayne Hutchings
    • Bita Hambrecht
    • Patrick Lüningschrör
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-18

  • The neuronal RNA-binding protein Ptbp2 is known to regulate neuronal differentiation by modulating alternative splicing. Here, the authors reveal an additional role of cytosolic Ptbp2, which regulates axon growth by fine-tuning the mRNA transport and local synthesis of an RNA-binding protein hnRNP R.

    • Saeede Salehi
    • Abdolhossein Zare
    • Michael Sendtner
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-19