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Advanced filters: Author: Abhineet Agarwal Clear advanced filters

  • Wang, Tang and colleagues develop the low-signal signed iterative random forest pipeline to investigate epistasis in the genetic control of cardiac hypertrophy, identifying epistatic variants near CCDC141, IGF1R, TTN and TNKS loci, and show that hypertrophy in induced pluripotent stem cell-derived cardiomyocytes is nonadditively influenced by interactions among CCDC141, TTN and IGF1R.

    • Qianru Wang
    • Tiffany M. Tang
    • Euan A. Ashley
    ResearchOpen Access
    Nature Cardiovascular Research
    Volume: 4, P: 740-760