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Showing 1–4 of 4 results
Advanced filters: Author: Abigail Jarret Clear advanced filters

  • In studies using mouse models of psoriasis, a spectrum of innate lymphoid cell types is reconfigured and converges via multiple trajectories on a type 3-like state, demonstrating the range and flexibility of innate lymphoid cell responses in the skin.

    • Piotr Bielecki
    • Samantha J. Riesenfeld
    • Richard A. Flavell
    Research
    Nature
    Volume: 592, P: 128-132

  • In mouse macrophages, a range of short and non-ATG-initiated open reading frames that can generate proteins are identified, one of which is shown to be essential for host immunity to enteric mucosal infection and inflammation.

    • Ruaidhrí Jackson
    • Lina Kroehling
    • Richard A. Flavell
    Research
    Nature
    Volume: 564, P: 434-438

  • Ram Savan and colleagues report that two miRNAs known to suppress type 3 interferon (IFN) signaling also downregulate type 1IFN signaling in hepatitis C virus (HCV)-infected hepatocytes. The findings provide insights into the mechanisms by which antiviral IFN signaling is inhibited in HCV infection.

    • Abigail Jarret
    • Adelle P McFarland
    • Ram Savan
    Research
    Nature Medicine
    Volume: 22, P: 1475-1481