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Showing 1–2 of 2 results
Advanced filters: Author: Ada Weinstock Clear advanced filters

  • In this Review, the authors present a roadmap towards achieving consensus on development, analysis and interpretation of single-cell transcriptomics data in adipose tissue, including discussion of roadblocks, best practices and ideal cell-type markers for annotation of adipose tissue cell types in mice and humans.

    • Anne Loft
    • Margo P. Emont
    • Evan D. Rosen
    Reviews
    Nature Metabolism
    Volume: 7, P: 875-894

  • Hypercholesterolemia and vascular inflammation both contribute to the pathogenesis of atherosclerosis, but how hypercholesterolemia initiates vascular inflammation is not fully understood. Here the authors report that crosstalk between macrophages and endothelial cells mediated by the cholesterol metabolite 27-hydroxycholesterol drives vascular inflammation and contributes to atherosclerosis in male mice.

    • Liming Yu
    • Lin Xu
    • Philip W. Shaul
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-17