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Showing 1–4 of 4 results
Advanced filters: Author: Adam D. Langenbacher Clear advanced filters

  • Myocardial contractile force and intracardiac hemodynamic shear stress coordinate the initiation of trabeculation in heart development. Here, the authors report that radially aligned myocardial strain activates snai1b+/Notch− cardiomyocytes, initiating delamination for trabeculation.

    • Jing Wang
    • Aaron L. Brown
    • Tzung K. Hsiai
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-16

  • Clonal ascidians are able to undergo whole body regeneration (WBR), where entire new bodies can be regenerated from blood vessel fragments. Here, the authors provide evidence in Botrylloides diegensis supporting pou3 and vasa expressing blood-borne cells isolated with anti-IA6 antibody as candidate stem cells responsible for WBR.

    • Susannah H. Kassmer
    • Adam D. Langenbacher
    • Anthony W. De Tomaso
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-11

  • The regulation of germ cell migration in the colonial ascidian Botryllus schlosseri is poorly understood. In this chordate, Kassmer et al. identify sphingosine-1-phosphate as regulating germ cell migration in vitroand homing of cells to newly developing bodies in live organisms.

    • Susannah H. Kassmer
    • Delany Rodriguez
    • Anthony W. De Tomaso
    ResearchOpen Access
    Nature Communications
    Volume: 6, P: 1-10

  • In teleosts, proper balance and hearing depend on mechanical sensors in the inner ear. These sensors include actin-based microvilli and microtubule-based cilia that extend from the surface of sensory hair cells and attach to biomineralized 'ear stones', orotoliths. This paper show that in zebra fish, fluid flow generated by cilia influences the number, growth and localization of otoliths, as well as their mineralization during development.

    • Jessica R. Colantonio
    • Julien Vermot
    • Kent L. Hill
    Research
    Nature
    Volume: 457, P: 205-209