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An Autogenously Regulated Expression System for Gene Therapeutic Ocular Applications

Matthew A. Sochor
Vidyullatha Vasireddy
Mitchell Lewis
ResearchOpen Access24 Nov 2015
Scientific Reports

Volume: 5, P: 1-8
Dynamic evolution of regulatory element ensembles in primate CD4⁺ T cells

It is unclear how evolutionary changes at enhancers affect the transcription of target genes. Measuring nascent transcription in CD4⁺ T cells in primates, the authors show that the effects of evolutionary changes in enhancers are buffered at the transcriptional level.

Charles G. Danko
Lauren A. Choate
Adam Siepel
Research29 Jan 2018
Nature Ecology & Evolution

Volume: 2, P: 537-548
Author Correction: An Autogenously Regulated Expression System for Gene Therapeutic Ocular Applications

Matthew A. Sochor
Vidyullatha Vasireddy
Mitchell Lewis
Amendments and CorrectionsOpen Access23 Nov 2018
Scientific Reports

Volume: 8, P: 1

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An Autogenously Regulated Expression System for Gene Therapeutic Ocular Applications

Dynamic evolution of regulatory element ensembles in primate CD4+ T cells

Author Correction: An Autogenously Regulated Expression System for Gene Therapeutic Ocular Applications

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Dynamic evolution of regulatory element ensembles in primate CD4⁺ T cells