The recent rise in obesity and its associated diseases has sparked intensive research into the transcriptional control of metabolic processes, collectively termed energy homeostasis. The authors review our current understanding of transcriptional and epigenetic regulators of energy homeostasis and crosstalk between pathways, and provide insights into emerging developments and challenges in this field.
- Adelheid Lempradl
- J. Andrew Pospisilik
- Josef M. Penninger