The cardiopharyngeal mesoderm gives rise to both heart and head musculature, though how these populations are specified remains less clear. Here they use mouse gastruloids to model cardiopharyngeal mesoderm specification and differentiation into both cardiac and skeletal muscle lineages, thus highlighting their potential for studying muscle development and congenital diseases.
- Laurent Argiro
- Céline Chevalier
- Fabienne Lescroart
