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Showing 1–2 of 2 results
Advanced filters: Author: Adi Bercovich-Kinori Clear advanced filters

  • Here, Israeli and Finkel et al. perform genome-wide CRISPR knockout screens to identify host factors required for the infection with SARS-CoV-2 and two additionally variants of concern, Alpha and Beta, unveiling shared and differential host pathways required by the variants, and demonstrate GATA6 is critical for SARS-CoV-2 viral entry through modulation of ACE2 expression.

    • Ma’ayan Israeli
    • Yaara Finkel
    • Adi Bercovich-Kinori
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-16

  • Here, Noy-Porat, Makdasi et al. report the isolation of a panel of neutralizing mAbs selected against SARS-CoV-2 receptor-binding domain (RBD) from a phage display library constructed based on patient samples collected in the acute phase of the disease, which show efficient neutralizing activities against authentic virus in vitro.

    • Tal Noy-Porat
    • Efi Makdasi
    • Ronit Rosenfeld
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-7