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Showing 1–2 of 2 results
Advanced filters: Author: Adrian Sanchez-Fernandez Clear advanced filters

  • Tuning protein solubilization in deep eutectic solvents (DESs) is useful for enhancing enzymatic reactions, preserving therapeutic biomolecules, and developing biomaterials, but it has only been demonstrated for a narrow range of anhydrous DESs. Here, using myoglobin as a case study, the authors show that surface modification can be used to solubilize proteins in both hydrophilic and hydrophobic DESs, with polarity and hydrogen bond capacity influencing the protein conformational state.

    • Adrian Sanchez-Fernandez
    • Jake H. Nicholson
    • Alex P. S. Brogan
    ResearchOpen Access
    Communications Chemistry
    Volume: 8, P: 1-7

  • The bottom-up reconstitution of natural filaments within simplified artificial cellular compartments, such as coacervates, offer a model to study, mimic, and potentially exploit cellular functions. Here, the authors summarize the latest developments towards assembling confined fibrillar networks inside coacervates and related compartments, including a selection of examples ranging from biological to fully synthetic building blocks.

    • Adrian Sanchez-Fernandez
    • Ignacio Insua
    • Javier Montenegro
    ReviewsOpen Access
    Communications Chemistry
    Volume: 7, P: 1-11