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Showing 1–6 of 6 results

Advanced filters: Author: Adriano Taddeo Clear advanced filters

SARS-CoV-2 spike D614G change enhances replication and transmission

A SARS-CoV-2 variant containing a D614G substitution in the spike protein shows enhanced binding to human ACE2, increased replication in human cell cultures and a competitive advantage in animal models of infection.

Bin Zhou
Tran Thi Nhu Thao
Martin Beer
Research26 Feb 2021
Nature

Volume: 592, P: 122-127
Enhanced fitness of SARS-CoV-2 variant of concern Alpha but not Beta

The Alpha variant of SARS-CoV-2 outcompetes progenitor SARS-CoV-2 in upper respiratory tract replication competition in vivo.

Lorenz Ulrich
Nico Joel Halwe
Charaf Benarafa
ResearchOpen Access22 Dec 2021
Nature

Volume: 602, P: 307-313
The spike gene is a major determinant for the SARS-CoV-2 Omicron-BA.1 phenotype

A comprehensive characterisation of Omicron-BA.1 and VOC Delta in numerous in vitro and in vivo models uncovers the factors that led to its global dominance.

G. Tuba Barut
Nico Joel Halwe
Volker Thiel
ResearchOpen Access07 Oct 2022
Nature Communications

Volume: 13, P: 1-14
A safe, effective and adaptable live-attenuated SARS-CoV-2 vaccine to reduce disease and transmission using one-to-stop genome modifications

A live-attenuated SARS-CoV-2 vaccine based on one-to-stop codon modifications can elicit broad, systemic and mucosal immunity, as well as reduced transmission of SARS-CoV-2 in vivo.

Jacob Schön
G. Tuba Barut
Volker Thiel
ResearchOpen Access12 Jul 2024
Nature Microbiology

Volume: 9, P: 2099-2112
Delivery of Rapamycin Using In Situ Forming Implants Promotes Immunoregulation and Vascularized Composite Allograft Survival

Damian Sutter
Dzhuliya V. Dzhonova
Jonas T. Schnider
ResearchOpen Access25 Jun 2019
Scientific Reports

Volume: 9, P: 1-16
Optimized intramuscular immunization with VSV-vectored spike protein triggers a superior immune response to SARS-CoV-2

Adriano Taddeo
Inês Berenguer Veiga
Gert Zimmer
ResearchOpen Access25 Jul 2022
npj Vaccines

Volume: 7, P: 1-15