Nature Search

Author Correction: A nascent riboswitch helix orchestrates robust transcriptional regulation through signal integration

Adrien Chauvier
Shiba S. Dandpat
Nils G. Walter
Amendments and CorrectionsOpen Access28 Feb 2025
Nature Communications

Volume: 16, P: 1
Transcriptional pausing at the translation start site operates as a critical checkpoint for riboswitch regulation

Riboswitches are non-coding RNA elements that detect metabolites and control expression by regulating mRNA levels or translation. Here, the authors provide evidence that theE. coli thiC riboswitch has a pause site in the translation initiation region that acts as a checkpoint for thiCexpression.

Adrien Chauvier
Frédéric Picard-Jean
Daniel A. Lafontaine
ResearchOpen Access10 Jan 2017
Nature Communications

Volume: 8, P: 1-12
Structural basis for control of bacterial RNA polymerase pausing by a riboswitch and its ligand

Using a combination of biochemical, structural and computational analyses, the authors unveil the mechanism of bacterial RNA polymerase pausing and restart mediated by a small-molecule-dependent RNA structural element termed a riboswitch.

Adrien Chauvier
Jason C. Porta
Nils G. Walter
Research01 Jun 2023
Nature Structural & Molecular Biology

Volume: 30, P: 902-913
A nascent riboswitch helix orchestrates robust transcriptional regulation through signal integration

Here the authors unveil an intermediate state during the folding of the manganese riboswitch from L. lactis. This transient state allows the integration of multiple cellular signals including RNA polymerase pausing and transcription factor NusA.

Adrien Chauvier
Shiba S. Dandpat
Nils G. Walter
ResearchOpen Access10 May 2024
Nature Communications

Volume: 15, P: 1-18
An anionic ligand snap-locks a long-range interaction in a magnesium-folded riboswitch

A single molecule fluorescence study revealed three dynamically interconverting conformations of the fluoride riboswitch from Bacillus cereus, where an anionic ligand snap-locks a docked conformation through a long-range interaction necessary for downstream gene regulation.

Rajeev Yadav
Julia R. Widom
Nils G. Walter
ResearchOpen Access11 Jan 2022
Nature Communications

Volume: 13, P: 1-13
Insights into the cotranscriptional and translational control mechanisms of the Escherichia coli tbpA thiamin pyrophosphate riboswitch

In vivo and in vitro studies of an Escherichia coli riboswitch highlights the role of cotranscriptional metabolite sensing and the mechanism of gene regulation.

Jonathan P. Grondin
Mélanie Geffroy
Daniel A. Lafontaine
ResearchOpen Access17 Oct 2024
Communications Biology

Volume: 7, P: 1-10

Search

Author Correction: A nascent riboswitch helix orchestrates robust transcriptional regulation through signal integration

Transcriptional pausing at the translation start site operates as a critical checkpoint for riboswitch regulation

Structural basis for control of bacterial RNA polymerase pausing by a riboswitch and its ligand

A nascent riboswitch helix orchestrates robust transcriptional regulation through signal integration

An anionic ligand snap-locks a long-range interaction in a magnesium-folded riboswitch

Insights into the cotranscriptional and translational control mechanisms of the Escherichia coli tbpA thiamin pyrophosphate riboswitch

Search

Quick links

Search

Filter By:

Author Correction: A nascent riboswitch helix orchestrates robust transcriptional regulation through signal integration

Transcriptional pausing at the translation start site operates as a critical checkpoint for riboswitch regulation

Structural basis for control of bacterial RNA polymerase pausing by a riboswitch and its ligand

A nascent riboswitch helix orchestrates robust transcriptional regulation through signal integration

An anionic ligand snap-locks a long-range interaction in a magnesium-folded riboswitch

Insights into the cotranscriptional and translational control mechanisms of the Escherichia coli tbpA thiamin pyrophosphate riboswitch

Search

Quick links