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Showing 1–3 of 3 results
Advanced filters: Author: Adrien Schahl Clear advanced filters

  • Azinas et al. report the cryo-EM structure of the MecA/ClpC/ClpP complex from Staphylococcus aureus, revealing how MecA forms a crown-like structure that likely facilitates substrate transfer to ClpC. They uncover asymmetric, activity-dependent interactions between ClpC and ClpP and demonstrate reciprocal allosteric regulation which enhances ATPase and proteolytic activity in bacterial AAA+ proteases.

    • Stavros Azinas
    • Karin Wallden
    • Marta Carroni
    ResearchOpen Access
    Communications Biology
    Volume: 8, P: 1-18

  • NMR structure calculations combined with molecular dynamics simulations suggest a conserved pre-structuration into coiled-coil dimers of the plant protein remorin before associating to the membrane.

    • Zeren Xu
    • Adrien Schahl
    • Birgit Habenstein
    ResearchOpen Access
    Communications Biology
    Volume: 7, P: 1-17