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Showing 1–3 of 3 results

Advanced filters: Author: Agnieszka Dejda Clear advanced filters

Therapeutic targeting of cellular senescence in diabetic macular edema: preclinical and phase 1 trial results

Small-molecule senolytic compounds targeting BCL-xL were beneficial in a mouse model of diabetic edema and well tolerated when tested in a phase 1 trial involving eight patients with diabetic macular edema.

Sergio Crespo-Garcia
Frédérik Fournier
Przemyslaw Sapieha
Research06 Feb 2024
Nature Medicine

Volume: 30, P: 443-454
Myeloid-resident neuropilin-1 influences brown adipose tissue in obesity

Roberto Diaz-Marin
Sergio Crespo-Garcia
Przemyslaw Sapieha
ResearchOpen Access03 Aug 2021
Scientific Reports

Volume: 11, P: 1-11
Effect of human very low-density lipoproteins on cardiotrophin-like cytokine factor 1 (CLCF1) activity

Sarah Pasquin
Salma Chehboun
Jean-François Gauchat
ResearchOpen Access05 Mar 2018
Scientific Reports

Volume: 8, P: 1-14