Using a rodent model of ischemic stroke, Zahgmi et al. report on the neuro-protective effects of a bioconjugate form of the glutamate scavenger, glutamate-oxaloacetate transaminase (GOT). They found that a single dose of the bioconjugate was more effective in reducing the infarct size and improving motor function than the native GOT due to its higher and long lasting blood activity.
- Ahlem Zaghmi
- Antonio Dopico-López
- Marc A. Gauthier
