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Showing 1–7 of 7 results

Advanced filters: Author: Aishan Zhao Clear advanced filters

Discovery and engineering of the antibody response to a prominent skin commensal

Staphylococcus epidermidis induces a potent, durable and specific antibody response that is conserved in humans and non-human primates, and which could be redirected against pathogens as a new form of topical vaccination.

Djenet Bousbaine
Katherine D. Bauman
Michael A. Fischbach
Research11 Dec 2024
Nature

Volume: 638, P: 1054-1064
Surface-attached molecules control Staphylococcus aureus quorum sensing and biofilm development

Covalent attachment of quorum-modulating peptides to surfaces can regulate Staphyloccocus aureus biofilm formation.

Minyoung Kevin Kim
Aishan Zhao
Bonnie L. Bassler
Research22 May 2017
Nature Microbiology

Volume: 2, P: 1-12
Local and global consequences of flow on bacterial quorum sensing

Quorum sensing (QS) systems in bacteria coordinate collective behaviour through the use of secreted signal molecules called autoinducers. Here, the authors identify conditions under which flow can activate or repress QS in S. aureus and V. cholera.

Minyoung Kevin Kim
François Ingremeau
Howard A. Stone
Research11 Jan 2016
Nature Microbiology

Volume: 1, P: 1-5
Mapping the T cell repertoire to a complex gut bacterial community

Germ-free mice were colonized with complex defined communities to show T cell recognition of commensals is focused on widely conserved, highly expressed cell-surface antigens, opening the door to new therapeutic strategies.

Kazuki Nagashima
Aishan Zhao
Michael A. Fischbach
Research16 Aug 2023
Nature

Volume: 621, P: 162-170
Evidence that ubiquitylated H2B corrals hDot1L on the nucleosomal surface to induce H3K79 methylation

The ubiquitylation of histone H2B on lysine 120 is an important modification with roles in a diverse range of nuclear processes. Here, the authors use 'designer' chromatin to show that H2B-ub orients hDot1L into the correct position for activation.

Linjiao Zhou
Matthew T. Holt
Tom W. Muir
ResearchOpen Access02 Feb 2016
Nature Communications

Volume: 7, P: 1-9
Improved variants of SrtA for site-specific conjugation on antibodies and proteins with high efficiency

Long Chen
Justin Cohen
Peng R. Chen
ResearchOpen Access18 Aug 2016
Scientific Reports

Volume: 6, P: 1-12
tRNA-derived fragment TRF365 regulates the metabolism of anterior cruciate ligament cells by targeting IKBKB

Dianbo Long
Yiyang Xu
Yan Kang
ResearchOpen Access10 Jan 2022
Cell Death Discovery

Volume: 8, P: 1-11