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Showing 1–2 of 2 results
Advanced filters: Author: Aiyuan Yang Clear advanced filters

  • In a new study Yingxian Li and her colleagues show that the microRNA miR-214 targets ATF4 in osteoblasts to negatively regulate their activity. Manipulating miR-214 levels experimentally showed that its elevated expression is sufficient to induce bone loss in mice and that its therapeutic inhibition reduces bone loss in two mouse models.

    • Xiaogang Wang
    • Baosheng Guo
    • Yingxian Li
    Research
    Nature Medicine
    Volume: 19, P: 93-100