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Showing 1–26 of 26 results

Advanced filters: Author: Akihisa Inoue Clear advanced filters

Structural and dynamic insights into the biased signaling mechanism of the human kappa opioid receptor

Kappa-opioid receptors (KORs) influence pain and itch. Here, using cryoEM, spectroscopy, and cell tests, the authors show how specific amino acids shape KOR responses. These findings may guide development of pain treatments with fewer side effects.

Chiyo Suno-Ikeda
Ryo Nishikawa
Ryoji Suno
ResearchOpen Access28 Oct 2025
Nature Communications

Volume: 16, P: 1-16
Wee1⁺-like gene in human cells

Makoto Igarashi
Akihisa Nagata
Hiroto Okayama
Research05 Sept 1991
Nature

Volume: 353, P: 80-83
Elongation factor-1α gene determines susceptibility to transformation

Masaaki Tatsuka
Hiromi Mitsui
Hiroto Okayama
Research24 Sept 1992
Nature

Volume: 359, P: 333-336
CAR T or NK cells targeting mismatched HLA-DR molecules in acute myeloid leukemia after allogeneic hematopoietic stem cell transplant

Ikeda et al. report that HLA-DRB1 can serve as a leukemia-specific target for CAR T or natural killer cell-based therapy in patients with AML after allogeneic hematopoietic stem cell transplantation.

Shunya Ikeda
Kana Hasegawa
Naoki Hosen
Research24 Mar 2025
Nature Cancer

Volume: 6, P: 595-611
A one-step fabrication of soft-magnetic high entropy alloy fiber with excellent strength and flexibility

Fe₃₄Co₂₉Ni₂₉Al₃Ta₃Si₂ high entropy alloy fibers with low coercivity and large plasticity are prepared. The fibers have a tensile strength of 674 MPa at 23% elongation, a coercivity of 8.1 Oe and a high Curie temperature of 770 K.

Yan Ma
Zongde Kou
Jiawei Li
ResearchOpen Access04 Dec 2024
Nature Communications

Volume: 15, P: 1-10
Cryo-EM structures of human zinc transporter ZnT7 reveal the mechanism of Zn²⁺ uptake into the Golgi apparatus

ZnT7 is a Golgi-localized Zn2 + /H+ antiporter. Here the authors present the cryo-EM structures of human ZnT7 in Zn2 + -bound and unbound forms, shedding light on its mechanism of Zn2+ transport.

Han Ba Bui
Satoshi Watanabe
Kenji Inaba
ResearchOpen Access08 Aug 2023
Nature Communications

Volume: 14, P: 1-16
Cobalt-based bulk glassy alloy with ultrahigh strength and soft magnetic properties

Akihisa Inoue
Baolong Shen
Alain R. Yavari
Research21 Sept 2003
Nature Materials

Volume: 2, P: 661-663
Direct observation of local atomic order in a metallic glass

The atomic configuration of metallic glasses is a long-standing issue important to the understanding of their properties. Nanobeam electron diffraction experiments now enable a direct determination of the local atomic order in a metallic glass.

Akihiko Hirata
Pengfei Guan
Mingwei Chen
Research21 Nov 2010
Nature Materials

Volume: 10, P: 28-33
Usefulness of a novel device to divide core needle biopsy specimens in a spatially matched fashion

Takumi Shiraishi
Shogo Inui
Osamu Ukimura
ResearchOpen Access13 Oct 2020
Scientific Reports

Volume: 10, P: 1-8
Mechanical properties and structural features of novel Fe-based bulk metallic glasses with unprecedented plasticity

Weiming Yang
Haishun Liu
Baolong Shen
ResearchOpen Access29 Aug 2014
Scientific Reports

Volume: 4, P: 1-6
Excellent capability in degrading azo dyes by MgZn-based metallic glass powders

Jun-Qiang Wang
Yan-Hui Liu
John H. Perepezko
ResearchOpen Access23 May 2012
Scientific Reports

Volume: 2, P: 1-6
Cryo-EM structures of the human volume-regulated anion channel LRRC8

Cryo-EM analyses of human LRRC8A show a homohexameric assembly that can adopt two conformations, compact or relaxed, indicating rigid-body motions that might be involved in channel gating.

Go Kasuya
Takanori Nakane
Osamu Nureki
Research20 Aug 2018
Nature Structural & Molecular Biology

Volume: 25, P: 797-804
STING signalling is terminated through ESCRT-dependent microautophagy of vesicles originating from recycling endosomes

Kuchitsu et al. show that STING-positive vesicles of a recycling endosome origin are encapsulated into lysosomes after STING ubiquitination and this process requires ESCRT proteins Tsg101 and Vps4.

Yoshihiko Kuchitsu
Kojiro Mukai
Tomohiko Taguchi
ResearchOpen Access13 Mar 2023
Nature Cell Biology

Volume: 25, P: 453-466
Publisher Correction: Defective Epstein–Barr virus in chronic active infection and haematological malignancy

Yusuke Okuno
Takayuki Murata
Hiroshi Kimura
Amendments and Corrections30 Jan 2019
Nature Microbiology

Volume: 4, P: 544
Alcohol consumption, genetic variants in the alcohol- and folate metabolic pathways and colorectal cancer risk: the JPHC Study

Thomas Svensson
Taiki Yamaji
Shoichiro Tsugane
ResearchOpen Access09 Nov 2016
Scientific Reports

Volume: 6, P: 1-8
Defective Epstein–Barr virus in chronic active infection and haematological malignancy

Genome sequencing of fractionated T-, B- and natural killer cells from patients with chronic active Epstein–Barr virus (EBV) infection sheds light on the nature of the EBV-infected progenitor and suggests a link between intragenic EBV deletions and EBV-associated neoplastic proliferations.

Yusuke Okuno
Takayuki Murata
Hiroshi Kimura
Research21 Jan 2019
Nature Microbiology

Volume: 4, P: 404-413
Cdc6 requires anchorage for its expression

Shigeki Jinno
Mika Yageta
Hiroto Okayama
Research08 Mar 2002
Oncogene

Volume: 21, P: 1777-1784
Author Correction: Helicobacter pylori infection, atrophic gastritis, and risk of pancreatic cancer: A population-based cohort study in a large Japanese population: the JPHC Study

Mayo Hirabayashi
Manami Inoue
Shoichiro Tsugane
Amendments and CorrectionsOpen Access28 Jul 2020
Scientific Reports

Volume: 10, P: 1
Traffic signal optimization on a square lattice with quantum annealing

Daisuke Inoue
Akihisa Okada
Hiroaki Yoshida
ResearchOpen Access10 Feb 2021
Scientific Reports

Volume: 11, P: 1-12
Specific localisation of ions in bacterial membranes unravels physical mechanism of effective bacteria killing by sanitiser

Judith Thoma
Wasim Abuillan
Motomu Tanaka
ResearchOpen Access23 Jul 2020
Scientific Reports

Volume: 10, P: 1-12
Perceived stress level and risk of cancer incidence in a Japanese population: the Japan Public Health Center (JPHC)-based Prospective Study

Huan Song
Eiko Saito
Shoichiro Tsugane
ResearchOpen Access11 Oct 2017
Scientific Reports

Volume: 7, P: 1-10
Individual HLAs influence immunological events in allogeneic stem cell transplantation from HLA-identical sibling donors

Satoko Morishima
Takahiro Fukuda
Kento Umino
Research09 Oct 2020
Bone Marrow Transplantation

Volume: 56, P: 646-654
Helicobacter pylori infection, atrophic gastritis, and risk of pancreatic cancer: A population-based cohort study in a large Japanese population: the JPHC Study

Mayo Hirabayashi
Manami Inoue
Shoichiro Tsugane
ResearchOpen Access15 Apr 2019
Scientific Reports

Volume: 9, P: 1-8
Composition Effect on Intrinsic Plasticity or Brittleness in Metallic Glasses

Yuan-Yun Zhao
Akihisa Inoue
Run-Wei Li
ResearchOpen Access21 Jul 2014
Scientific Reports

Volume: 4, P: 1-9
Nanoporous CuS with excellent photocatalytic property

Wence Xu
Shengli Zhu
Akihisa Inoue
ResearchOpen Access09 Dec 2015
Scientific Reports

Volume: 5, P: 1-11
Body mass index change during adulthood and risk of oesophageal squamous-cell carcinoma in a Japanese population: the Japan Public Health (JPHC)-based prospective study

Huan Song
Eiko Saito
Shoichiro Tsugane
ResearchOpen Access26 Sept 2017
British Journal of Cancer

Volume: 117, P: 1715-1722

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Structural and dynamic insights into the biased signaling mechanism of the human kappa opioid receptor

Wee1⁺-like gene in human cells

Elongation factor-1α gene determines susceptibility to transformation

CAR T or NK cells targeting mismatched HLA-DR molecules in acute myeloid leukemia after allogeneic hematopoietic stem cell transplant

A one-step fabrication of soft-magnetic high entropy alloy fiber with excellent strength and flexibility

Cryo-EM structures of human zinc transporter ZnT7 reveal the mechanism of Zn²⁺ uptake into the Golgi apparatus

Cobalt-based bulk glassy alloy with ultrahigh strength and soft magnetic properties

Direct observation of local atomic order in a metallic glass

Usefulness of a novel device to divide core needle biopsy specimens in a spatially matched fashion

Mechanical properties and structural features of novel Fe-based bulk metallic glasses with unprecedented plasticity

Excellent capability in degrading azo dyes by MgZn-based metallic glass powders

Cryo-EM structures of the human volume-regulated anion channel LRRC8

STING signalling is terminated through ESCRT-dependent microautophagy of vesicles originating from recycling endosomes

Publisher Correction: Defective Epstein–Barr virus in chronic active infection and haematological malignancy

Alcohol consumption, genetic variants in the alcohol- and folate metabolic pathways and colorectal cancer risk: the JPHC Study

Defective Epstein–Barr virus in chronic active infection and haematological malignancy

Cdc6 requires anchorage for its expression

Author Correction: Helicobacter pylori infection, atrophic gastritis, and risk of pancreatic cancer: A population-based cohort study in a large Japanese population: the JPHC Study

Traffic signal optimization on a square lattice with quantum annealing

Specific localisation of ions in bacterial membranes unravels physical mechanism of effective bacteria killing by sanitiser

Perceived stress level and risk of cancer incidence in a Japanese population: the Japan Public Health Center (JPHC)-based Prospective Study

Individual HLAs influence immunological events in allogeneic stem cell transplantation from HLA-identical sibling donors

Helicobacter pylori infection, atrophic gastritis, and risk of pancreatic cancer: A population-based cohort study in a large Japanese population: the JPHC Study

Composition Effect on Intrinsic Plasticity or Brittleness in Metallic Glasses

Nanoporous CuS with excellent photocatalytic property

Body mass index change during adulthood and risk of oesophageal squamous-cell carcinoma in a Japanese population: the Japan Public Health (JPHC)-based prospective study

Search

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