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Communications Biology (2)
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Advanced filters: Author: Akshay Gurdita Clear advanced filters

SNAP-25, but not SNAP-23, is essential for photoreceptor development, survival, and function in mice

A study using photoreceptor-specific knockout mice finds that SNAP-25, and not SNAP-23, is the isoform crucial for photoreceptor development, survival, and function. Mechanistically, SNAP-25 mediates photopigment trafficking and synaptic functioning.

Mengjia Huang
Chun Hin Chow
Shuzo Sugita
ResearchOpen Access05 Jan 2024
Communications Biology

Volume: 7, P: 1-14
Three dimensional reconstruction of the mouse cerebellum in Hedgehog-driven medulloblastoma models to identify Norrin-dependent effects on preneoplasia

Light sheet fluorescent microscopy can successfully be used to quantify preneoplastic alteration of tissue in mouse medulloblastoma, providing an alternative approach for 3D analysis of tumour initiation events in mice.

Nenad T. Pokrajac
Akshay Gurdita
Valerie A. Wallace
ResearchOpen Access09 Jun 2022
Communications Biology

Volume: 5, P: 1-11
Morphological and functional changes in the rat retina associated with 2 months of intermittent moderate intraocular pressure elevation

Bingyao Tan
Akshay Gurdita
Kostadinka Bizheva
ResearchOpen Access16 May 2018
Scientific Reports

Volume: 8, P: 1-11

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