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Showing 1–2 of 2 results
Advanced filters: Author: Akshay Sanghi Clear advanced filters

  • Studies show the cancer transcriptome correlates poorly with the cancer proteome, questioning the role of chromatin regulation. Here the authors demonstrate proximal-gene-body chromatin elements and transcription predict abundances of differentially expressed proteins in thyroid and breast cancers.

    • Akshay Sanghi
    • Joshua J. Gruber
    • Michael P. Snyder
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-14

  • A map of cohesin-mediated chromatin loops in 24 types of human cells identifies loops that show cell-type-specific variation, indicating that chromatin loops may help to specify cell-specific gene expression programs and functions.

    • Fabian Grubert
    • Rohith Srivas
    • Michael Snyder
    ResearchOpen Access
    Nature
    Volume: 583, P: 737-743