The authors find that the homeobox gene Dbx1 controls the fate of glutamatergic neurons in the preBötzinger complex (preBötC) that are indispensable for the generation of the respiratory rhythm. Establishment of commissural connections between the halves of the preBötC, which is critical for synchronous discharge, requires Robo3 expression by these neurons.
- Julien Bouvier
- Muriel Thoby-Brisson
- Gilles Fortin