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Showing 1–4 of 4 results
Advanced filters: Author: Albinas Cepauskas Clear advanced filters

  • Toxic small alarmone synthetase (toxSAS) enzymes are toxic effectors of certain toxin–antitoxin modules, involved in phage defense and secretion systems. Here the authors establish the mechanism underlying toxSAS inhibition by structured antitoxins and reveal the connection between neutralization strategy and substrate specificity.

    • Lucia Dominguez-Molina
    • Tatsuaki Kurata
    • Abel Garcia-Pino
    ResearchOpen Access
    Nature Chemical Biology
    Volume: 21, P: 182-192

  • The antiphage defence protein CapRelSJ46 in Escherichia coli can directly bind and sense two completely unrelated and structurally different proteins using the same sensory domain, with overlapping but distinct interfaces.

    • Tong Zhang
    • Albinas Cepauskas
    • Michael T. Laub
    ResearchOpen Access
    Nature
    Volume: 635, P: 728-735