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Tissue-resident macrophage survival depends on mitochondrial function regulated by SerpinB2 in chronic inflammation

How cellular metabolism influences tissue-resident macrophage survival is currently unknown. The authors here demonstrate that SerpinB2 regulates mitochondrial function to promote tissue-resident macrophage survival.

Sathish Babu Vasamsetti
Samreen Sadaf
Partha Dutta
ResearchOpen Access12 Feb 2026
Nature Communications

Volume: 17, P: 1-23

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Tissue-resident macrophage survival depends on mitochondrial function regulated by SerpinB2 in chronic inflammation

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