Nature Search

EWS::FLI1 expression in human embryonic mesenchymal stem cells leads to transcriptional reprograming, defective DNA damage repair and Ewing sarcoma

Ewing sarcoma (ES) is characterized by EWSR1/ETS gene rearrangements with unknown cellular origin. Here, authors show that expressing the EWS::FLI1 oncogene in human embryonic mesenchymal stem cells induces an Ewing sarcoma-like transcriptome and forms tumors in mice.

Inmaculada Hernández-Muñoz
Irene Cuervas
Jaume Mora
ResearchOpen Access24 Oct 2025
Nature Communications

Volume: 16, P: 1-21
New genetic diagnoses for inherited retinal dystrophies by integrating splicing tools into NGS pipelines

Elena Fernández-Suárez
María González-del Pozo
Guillermo Antiñolo
ResearchOpen Access02 Jul 2025
npj Genomic Medicine

Volume: 10, P: 1-15
The first wave of the COVID-19 epidemic in Spain was associated with early introductions and fast spread of a dominating genetic variant

Analysis of 2,170 SARS-CoV-2 sequences from the first wave of the COVID-19 epidemic in Spain provides insights into transmission patterns and the effects of lockdown on the emergence of new variants.

Mariana G. López
Álvaro Chiner-Oms
Iñaki Comas
Research30 Sept 2021
Nature Genetics

Volume: 53, P: 1405-1414
Parkinson’s disease medication adjustments based on wearable device information compared to other methods: randomized clinical trial

Alejandro Rodríguez-Molinero
Carlos Pérez-López
Antonio Miñarro
ResearchOpen Access20 Aug 2025
npj Parkinson's Disease

Volume: 11, P: 1-9
Genotypic variations in leaf and whole-plant water use efficiencies are closely related in bread wheat genotypes under well-watered and water-limited conditions during grain filling

Alejandro del Pozo
Ana María Méndez-Espinoza
Gustavo A. Lobos
ResearchOpen Access16 Jan 2020
Scientific Reports

Volume: 10, P: 1-13
LRH-1 agonism favours an immune-islet dialogue which protects against diabetes mellitus

Type 1 diabetes mellitus (T1DM) is characterized by beta cell loss because of an autoimmune attack. Here the authors show that an agonist for LRH-1/NR5A2, a nuclear receptor known to be protective against beta cell apoptosis, inhibits immune-mediated inflammation and hyperglycemia in T1DM mouse models.

Nadia Cobo-Vuilleumier
Petra I. Lorenzo
Benoit R. Gauthier
ResearchOpen Access16 Apr 2018
Nature Communications

Volume: 9, P: 1-15
Apoplastic class III peroxidases PRX62 and PRX69 promote Arabidopsis root hair growth at low temperature

Arabidopsis root hair growth is enhanced at low temperatures. Here the authors show that the class III peroxidases PRX62 and PRX69 modulate ROS homeostasis and cell wall characteristics, and promote root hair elongation at low temperature.

Javier Martínez Pacheco
Philippe Ranocha
José M. Estevez
ResearchOpen Access14 Mar 2022
Nature Communications

Volume: 13, P: 1-14
Optimization-based design of an elastostatic cloaking device

Víctor D. Fachinotti
Ignacio Peralta
Alejandro E. Albanesi
ResearchOpen Access29 Jun 2018
Scientific Reports

Volume: 8, P: 1-8
Humoral and cellular immune response over 9 months of mRNA-1273, BNT162b2 and ChAdOx1 vaccination in a University Hospital in Spain

Leire Fernández-Ciriza
Álvaro González
Gabriel Reina
ResearchOpen Access07 Oct 2022
Scientific Reports

Volume: 12, P: 1-10
Comparison of seven prognostic tools to identify low-risk pulmonary embolism in patients aged <50 years

Luis Jara-Palomares
Maria Alfonso
Abilio Reis
ResearchOpen Access27 Dec 2019
Scientific Reports

Volume: 9, P: 1-10
Ecotypic differentiation and phenotypic plasticity combine to enhance the invasiveness of the most widespread daisy in Chile, Leontodon saxatilis

Irene Martín-Forés
Marta Avilés
Miguel A. Casado
ResearchOpen Access08 May 2017
Scientific Reports

Volume: 7, P: 1-10
BIM-23A760 influences key functional endpoints in pituitary adenomas and normal pituitaries: molecular mechanisms underlying the differential response in adenomas

Alejandro Ibáñez-Costa
Laura M. López-Sánchez
Raúl M. Luque
ResearchOpen Access09 Feb 2017
Scientific Reports

Volume: 7, P: 1-14

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EWS::FLI1 expression in human embryonic mesenchymal stem cells leads to transcriptional reprograming, defective DNA damage repair and Ewing sarcoma

New genetic diagnoses for inherited retinal dystrophies by integrating splicing tools into NGS pipelines

The first wave of the COVID-19 epidemic in Spain was associated with early introductions and fast spread of a dominating genetic variant

Parkinson’s disease medication adjustments based on wearable device information compared to other methods: randomized clinical trial

Genotypic variations in leaf and whole-plant water use efficiencies are closely related in bread wheat genotypes under well-watered and water-limited conditions during grain filling

LRH-1 agonism favours an immune-islet dialogue which protects against diabetes mellitus

Apoplastic class III peroxidases PRX62 and PRX69 promote Arabidopsis root hair growth at low temperature

Optimization-based design of an elastostatic cloaking device

Humoral and cellular immune response over 9 months of mRNA-1273, BNT162b2 and ChAdOx1 vaccination in a University Hospital in Spain

Comparison of seven prognostic tools to identify low-risk pulmonary embolism in patients aged <50 years

Ecotypic differentiation and phenotypic plasticity combine to enhance the invasiveness of the most widespread daisy in Chile, Leontodon saxatilis

BIM-23A760 influences key functional endpoints in pituitary adenomas and normal pituitaries: molecular mechanisms underlying the differential response in adenomas

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