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Showing 1–3 of 3 results
Advanced filters: Author: Aleksandra Vancevska Clear advanced filters

  • ~15% of cancers induce alternative lengthening of telomeres (ALT) to activate telomere maintenance. Here, the authors reveal that infection with Kaposi’s sarcoma herpesvirus (KSHV) induces acquisition of ALT-like features in previously non-ALT cell lines.

    • Timothy P. Lippert
    • Paulina Marzec
    • Simon J. Boulton
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-11

  • Single-stranded DNA during DNA replication and repair in S/G2 needs protection by replication protein A (RPA). Here the authors reveal that RPA also shields inherited single-stranded DNA in G1, representing replication remnants from the previous cell cycle, to allow for post-mitotic DNA synthesis.

    • Aleksandra Lezaja
    • Andreas Panagopoulos
    • Matthias Altmeyer
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-15