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Showing 1–5 of 5 results
Advanced filters: Author: Aleksandre Japaridze Clear advanced filters

  • Bacterial chromosomes are tightly packed, limiting structural analysis by imaging techniques. Here, by quantitative time-lapse single-cell imaging of widened Escherichia coli cells, Wu and Japaridze et al. show that the chromosome exhibits a ring-like torus topology and a dynamic domain structure.

    • Fabai Wu
    • Aleksandre Japaridze
    • Cees Dekker
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-9

  • Motion is a key characteristic of every form of life. In this work, the authors use graphene drums to probe the nanomotion of a single bacterium and develop a new way for performing antibiotic susceptibility testing with single-cell resolution.

    • Irek E. Rosłoń
    • Aleksandre Japaridze
    • Farbod Alijani
    Research
    Nature Nanotechnology
    Volume: 17, P: 637-642

  • The spatial structure of the bacterial chromosome is resolved in the absence of confinement by the cell boundary. Size-expanded cells reveal a crescent-shaped Bacillus subtilis chromosome and the effects of ParB and SMC proteins on chromosome shape.

    • Miloš Tišma
    • Florian Patrick Bock
    • Cees Dekker
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-13

  • How chromosome replication and segregation is organised in E. coli is a matter of debate. Here the authors visualise the bacterial chromosome and the replisomes during DNA replication, providing support for a previously suggested train track model.

    • Aleksandre Japaridze
    • Christos Gogou
    • Cees Dekker
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-10