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Showing 1–7 of 7 results
Advanced filters: Author: Alessandro Soncini Clear advanced filters

  • Gaining a better understanding of the complex electronic structure of single-molecule magnets is essential for their design and development. The 4f-electron density distribution of a dysprosium single-molecule magnet has now been experimentally determined using synchrotron diffraction data interpreted with a multipole model. The magnetic easy axes were recovered by analysis of the 4f-electron density shape, which is clearly oblate.

    • Chen Gao
    • Alessandro Genoni
    • Jacob Overgaard
    Research
    Nature Chemistry
    Volume: 12, P: 213-219

  • Leukaemia development has been reported as an associated risk of haematopoietic stem cell gene therapy (HSPC-GT) using retroviral vectors in different diseases. Here, the authors show a case of T-cell acute lymphoid leukaemia in a patient with Adenosine Deaminase-deficient Severe Combined Immunodeficiency (ADA-SCID) treated with retroviral gene therapy.

    • Daniela Cesana
    • Maria Pia Cicalese
    • Alessandro Aiuti
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-18

  • Fifteen years’ follow-up of clinical development and real-world data from 43 patients show that gammaretroviral gene therapy for adenosine deaminase deficiency has a positive long-term efficacy profile, warranting continued safety monitoring of patients receiving gene therapy.

    • Maddalena Migliavacca
    • Federica Barzaghi
    • Maria Pia Cicalese
    Research
    Nature Medicine
    Volume: 30, P: 488-497

  • Understanding the anisotropic electronic structure of lanthanide complexes is useful for a range of advanced applications. Here, the authors present a simple electrostatic method, capable of predicting the magnetic anisotropy of low-symmetry mononuclear and polynuclear dysprosium(III) complexes.

    • Nicholas F. Chilton
    • David Collison
    • Alessandro Soncini
    Research
    Nature Communications
    Volume: 4, P: 1-7

  • Haematopoietic stem cell (HSC) clonogenic activity, lineage output, lineage commitment and somatic mutation rates are influenced by the underlying disease, patient age, extent of genetic defect correction and hematopoietic stress imposed by the inherited disease, suggesting HSC adaptation.

    • Andrea Calabria
    • Giulio Spinozzi
    • Eugenio Montini
    ResearchOpen Access
    Nature
    Volume: 636, P: 162-171

  • Coupling molecular toroids via ferrotoroidic interactions represents an important opportunity to enhance ground state toroidicity, but is challenging to achieve. Here the authors isolate a {CrIIIDyIII 6} complex with a ferrotoroidic ground state and an enhanced toroidal moment, arising solely from intramolecular dipolar interactions.

    • Kuduva R. Vignesh
    • Alessandro Soncini
    • Gopalan Rajaraman
    ResearchOpen Access
    Nature Communications
    Volume: 8, P: 1-12