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Showing 1–4 of 4 results
Advanced filters: Author: Alessio De Magis Clear advanced filters

  • G4 structure-interacting proteins have been linked to DNA repair processes. Here the authors reveal that in yeast, Zuo1 associates with G4 structures and plays a role in repair pathway choice by promoting nucleotide excision repair and ultimately contributing to maintenance of genome stability.

    • Alessio De Magis
    • Silvia Götz
    • Katrin Paeschke
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-12

  • Senescence can be activated in a DNA damage-dependent and -independent manner. Here the authors reveal in cell lines that recruitment of the factor ZRF1 at G4 DNA structures can prevents UV-induced senescence.

    • Alessio De Magis
    • Michaela Limmer
    • Katrin Paeschke
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-16

  • The homologous recombination machinery needs to be recruited at replication intermediates for accurate functioning. Here, the authors reveal that a Rad51 paralog-containing complex, called the Shu complex, recognizes and enables tolerance of predominantly lagging strand abasic sites.

    • Joel C. Rosenbaum
    • Braulio Bonilla
    • Kara A. Bernstein
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-11