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Advanced filters: Author: Alex Bortvin Clear advanced filters

  • Mammals lose up to 80% of their finite oocyte supply during fetal development. Here the authors interrogate mechanisms of fetal oocyte attrition in mice, driven by the simultaneous upregulation of LINE-1 retrotransposon activity and inhibit these mechanisms to increase the functional ovarian reserve.

    • Marla E. Tharp
    • Safia Malki
    • Alex Bortvin
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-13