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Showing 1–4 of 4 results
Advanced filters: Author: Alex J. H. Fedorec Clear advanced filters

  • Bacteriocins are antimicrobial peptides that are naturally produced by many bacteria. In this work, authors develop a bacteriocin secretion platform, and test, in a proof-of-concept study, antimicrobial efficacy against Enterococcus faecalis and Enterococcus faecium.

    • Jack W. Rutter
    • Linda Dekker
    • Chris P. Barnes
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-12

  • Biological computing is a promising field with potential applications in biosafety, environmental monitoring, and personalized medicine. Here the authors create bio-computers using engineered E. coli colonies that respond to chemical gradients, producing different logic functions depending on how they are spatially arranged.

    • Alex J. H. Fedorec
    • Neythen J. Treloar
    • Chris P. Barnes
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-11

  • Engineered microbial communities can divide labour between their members and interface with natural microbiomes. Here the authors demonstrate how a single toxin producing engineered strain can tune the composition of a two-strain community.

    • Alex J. H. Fedorec
    • Behzad D. Karkaria
    • Chris P. Barnes
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-12

  • In naturally occurring microbial systems, there is a positive relationship between species diversity and productivity of the community. Here the authors perform model selection to find potential amensal interactions that yield robust stable synthetic microbial consortia.

    • Behzad D. Karkaria
    • Alex J. H. Fedorec
    • Chris P. Barnes
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-12