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PARTNER cohort A—TAVR is an option for operable severe aortic stenosis

Alexandra King
Research Highlights21 Jun 2011
Nature Reviews Cardiology

Volume: 8, P: 422
SAMHD1 acts at stalled replication forks to prevent interferon induction

SAMHD1 has an essential role in the replication stress response and prevents inflammation by activating the MRE11 nuclease to degrade nascent DNA strands at stalled replication forks, thus enabling replication.

Flavie Coquel
Maria-Joao Silva
Philippe Pasero
Research18 Apr 2018
Nature

Volume: 557, P: 57-61

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PARTNER cohort A—TAVR is an option for operable severe aortic stenosis

SAMHD1 acts at stalled replication forks to prevent interferon induction

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