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Showing 1–11 of 11 results
Advanced filters: Author: Alexandre J. Kabla Clear advanced filters

  • Tissue monolayers avoid rupture at large tensile stresses through a strain-stiffening process governed by intermediate keratin filaments.

    • Julia Duque
    • Alessandra Bonfanti
    • Guillaume Charras
    ResearchOpen Access
    Nature Materials
    Volume: 23, P: 1563-1574

  • Stress relaxation in cell monolayers shows remarkable similarities with that of single cells, suggesting the rheology of epithelial tissues is mediated by the actomyosin cortex—with dynamics reminiscent of those on a cellular level.

    • Nargess Khalilgharibi
    • Jonathan Fouchard
    • Guillaume Charras
    Research
    Nature Physics
    Volume: 15, P: 839-847

  • Epithelial tissues behave as pre-tensed viscoelastic sheets that can buffer against compression and rapidly recover from buckling. Epithelial mechanical properties define a tissue-intrinsic buckling threshold that dictates the compressive strain above which tissue folds become permanent.

    • Tom P. J. Wyatt
    • Jonathan Fouchard
    • Guillaume T. Charras
    Research
    Nature Materials
    Volume: 19, P: 109-117

  • As tissues mature, they undergo shape changes that are the result of individual and collective cell movement triggered by cell-autonomous behavior or external forces. By measuring patterns of strain rates the authors can model these forces and quantify tissue shaping behavior.

    • Guy B Blanchard
    • Alexandre J Kabla
    • Richard J Adams
    Research
    Nature Methods
    Volume: 6, P: 458-464

  • When exiting pluripotency but before irreversibly committing, embryonic stem cells pass through at least one transition state. It is now shown that in this metastable state the nuclei of the cells is auxetic, that is, when stretched their cross-section expands, and when compressed their cross-section contracts, and that this is in part a consequence from global chromatin de-condensation.

    • Stefano Pagliara
    • Kristian Franze
    • Kevin J. Chalut
    Research
    Nature Materials
    Volume: 13, P: 638-644

  • Epithelial wound closure proceeds through both crawling into the wound and by constricting an actomyosin cable in a so-called purse-string mechanism. Here the authors show that the two mechanisms are mechanically coupled and the curvature of the wound regulates the overall dynamics of wound closure.

    • Andrea Ravasio
    • Ibrahim Cheddadi
    • Benoit Ladoux
    ResearchOpen Access
    Nature Communications
    Volume: 6, P: 1-13

  • Drosophila germ-band extension is thought to rely mainly on cell intercalation events. Quantitative analysis of cell shape changes and movements show that extrinsic tensile forces generated by the invaginating mesoderm drive cell shape changes to participate in this elongation.

    • Lucy C. Butler
    • Guy B. Blanchard
    • Benedicte Sanson
    Research
    Nature Cell Biology
    Volume: 11, P: 859-864