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Advanced filters: Author: Alexandros Papagiannakis Clear advanced filters

Temporal segregation of biosynthetic processes is responsible for metabolic oscillations during the budding yeast cell cycle

Takhaveev et al. use single-cell methods and mathematical modeling to reveal distinct waves in the synthesis rates of proteins, lipids and polysaccharides during the budding yeast cell cycle and relate them to flux changes in primary metabolism.

Vakil Takhaveev
Serdar Özsezen
Matthias Heinemann
ResearchOpen Access27 Feb 2023
Nature Metabolism

Volume: 5, P: 294-313
Differential scaling between G1 protein production and cell size dynamics promotes commitment to the cell division cycle in budding yeast

By measuring metabolic and biosynthetic activity with cell cycle progression, Litsios et el. uncover pulses in protein production rate that do not scale with cell size but drive cell cycle entry in budding yeast.

Athanasios Litsios
Daphne H. E. W. Huberts
Matthias Heinemann
Research04 Nov 2019
Nature Cell Biology

Volume: 21, P: 1382-1392
Quantitative characterization of the auxin-inducible degron: a guide for dynamic protein depletion in single yeast cells

Alexandros Papagiannakis
Janeska J de Jonge
Matthias Heinemann
ResearchOpen Access05 Jul 2017
Scientific Reports

Volume: 7, P: 1-13