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Showing 1–3 of 3 results
Advanced filters: Author: Alexej Kedrov Clear advanced filters

  • The pathogen Pseudomonas aeruginosa uses a membrane complex, PelBC, to produce exopolysaccharides for biofilm formation. Here the authors combine structural analysis, simulations and single-channel recordings of PelBC to provide a detailed view on its unique architecture and dynamics, and reveal the export route for the polysaccharide.

    • Marius Benedens
    • Cristian Rosales-Hernandez
    • Alexej Kedrov
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-16

  • Class I lantibiotic dehydratases play a key role in the biosynthesis of ribosomally synthesized peptide antibiotics. We present structural insights into MadB in two states, revealing the conformational changes that underlie its catalytic mechanism during maddinglicin maturation.

    • C. Vivien Knospe
    • Julio Ortiz
    • Lutz Schmitt
    ResearchOpen Access
    Communications Biology
    Volume: 8, P: 1-12