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Nature Ecology & Evolution (2)
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Advanced filters: Author: Alfonso Santos-Lopez Clear advanced filters

Plasmid-encoded insertion sequences promote rapid adaptation in clinical enterobacteria

Combining experimental and within-patient evolution analyses, the authors show that the widespread conjugative plasmid pOXA-48 promotes bacterial evolution through the transposition of plasmid-encoded insertion sequence IS1 elements.

Jorge Sastre-Dominguez
Javier DelaFuente
Alvaro San Millan
Research28 Aug 2024
Nature Ecology & Evolution

Volume: 8, P: 2097-2112
Within-patient evolution of plasmid-mediated antimicrobial resistance

A combination of analysis of plasmid diversity in the gut of hospitalized patients with experimental evolution shows that the evolution of plasmid-mediated antibiotic resistance involves a trade-off between antibiotic resistance levels and bacterial fitness.

Javier DelaFuente
Laura Toribio-Celestino
Alvaro San Millan
Research27 Oct 2022
Nature Ecology & Evolution

Volume: 6, P: 1980-1991
Prevalence and factors linked to renal involvement in prediabetes patients across Europe in the ePREDICE trial

Sebastián Mas-Fontao
Esther Civantos
Jesús Egido
ResearchOpen Access05 Dec 2024
Scientific Reports

Volume: 14, P: 1-15