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Cell Death & Disease (1)
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Advanced filters: Author: Ali A. Abdul-Sater Clear advanced filters

The signaling adaptor TRAF1 negatively regulates Toll-like receptor signaling and this underlies its role in rheumatic disease

The signaling adaptor TRAF1 is involved in TNFR-induced survival. Watts and colleagues demonstrate that TRAF1 also negatively regulates NF-κB activation by interfering with linear ubiquitination of the signaling subunit NEMO.

Ali A Abdul-Sater
Maria I Edilova
Tania H Watts
Research28 Nov 2016
Nature Immunology

Volume: 18, P: 26-35
Autophagy deficiency exacerbates iron overload induced reactive oxygen species production and apoptotic cell death in skeletal muscle cells

Hye Kyoung Sung
Mayoorey Murugathasan
Gary Sweeney
ResearchOpen Access07 Apr 2023
Cell Death & Disease

Volume: 14, P: 1-13

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The signaling adaptor TRAF1 negatively regulates Toll-like receptor signaling and this underlies its role in rheumatic disease

Autophagy deficiency exacerbates iron overload induced reactive oxygen species production and apoptotic cell death in skeletal muscle cells

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