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Showing 1–2 of 2 results
Advanced filters: Author: Alice Budden Clear advanced filters

  • DNA2 suppresses recombination-restarted replication and checkpoint activation at stalled forks, and its loss triggers recombination-dependent synthesis, checkpoint signalling and cell-cycle exit, highlighting its essential role in proliferation and growth failure in primordial dwarfism.

    • Jessica J. R. Hudson
    • Rowin Appanah
    • Ulrich Rass
    ResearchOpen Access
    Nature
    Volume: 646, P: 992-1000

  • Replication forks that are stalled at obstacles on the DNA template can be restarted by homologous recombination. Here, the authors show replication dynamics during homologous recombination-dependent replication fork restart by combining polymerase usage sequencing and a Monte Carlo mathematical model.

    • Karel Naiman
    • Eduard Campillo-Funollet
    • Antony M. Carr
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-11