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Advanced filters: Author: Alice Pavlowsky Clear advanced filters

Glia fuel neurons with locally synthesized ketone bodies to sustain memory under starvation

In the Drosophila starved brain, memory formation undergoes adaptive plasticity. Silva et al. show that neurons in the olfactory memory centre of the starved fly are fuelled by glial-derived ketone bodies in order to sustain memory formation.

Bryon Silva
Olivier L. Mantha
Thomas Preat
ResearchOpen Access17 Feb 2022
Nature Metabolism

Volume: 4, P: 213-224
Neuronal fatty acid oxidation fuels memory after intensive learning in Drosophila

Neurons are shown to use fatty acid β-oxidation as a fuel source for memory formation upon intensive learning in Drosophila, challenging the view that neurons are unable to use fatty acids for energy production.

Alice Pavlowsky
Bryon Silva
Thomas Preat
ResearchOpen Access10 Dec 2025
Nature Metabolism

Volume: 7, P: 2438-2450
Learning-induced and stathmin-dependent changes in microtubule stability are critical for memory and disrupted in ageing

The microtubule-associated protein stathmin is implicated in cognitive processing but it is unclear how. Here, the authors show that stathmin regulates microtubule stability and dendritic transport of specific AMPA receptor subunits, and that this regulation is impaired in aged mice.

Shusaku Uchida
Guillaume Martel
Gleb P. Shumyatsky
Research10 Jul 2014
Nature Communications

Volume: 5, P: 1-13

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