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Showing 1–2 of 2 results
Advanced filters: Author: Alicia Steffens Clear advanced filters

  • Meningiomas are common brain tumors with variable behavior. This study reveals high STING expression across multiple cell types in the meningioma microenvironment. STING agonism triggers tumor cell death via programmed necrosis and pyroptosis, enhancing survival in preclinical models.

    • Mark W. Youngblood
    • Shashwat Tripathi
    • Amy B. Heimberger
    ResearchOpen Access
    Nature Communications
    Volume: 17, P: 1-19

  • Observation of glioblastoma invasion in subcortical brain regions is challenging. Here the authors develop a Deep3P workflow to enable longitudinal deep imaging of glioblastoma and its microenvironment by combining three-photon microscopy and deep learning-based analysis, unraveling the invasion routes of these tumor cells into and within the white matter.

    • Marc Cicero Schubert
    • Stella Judith Soyka
    • Varun Venkataramani
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-21