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Showing 1–2 of 2 results
Advanced filters: Author: Alina Janney Clear advanced filters

  • Studies in mice show that effector T regulatory cells in the gut are most functional in the lamina propria, but this homeostatic niche is disrupted in inflammation, suggesting a spatial mechanism of tolerance to commensal microorganisms.

    • Yisu Gu
    • Raquel Bartolomé-Casado
    • Fiona Powrie
    ResearchOpen Access
    Nature
    Volume: 628, P: 854-862

  • This Review describes the interplay between host genetics, host immunity and the gut microbiome in the modulation of colorectal cancer, and discusses the role of specific bacterial species and metabolites alongside technological advances that will facilitate more in-depth investigation of the microbiome in disease.

    • Alina Janney
    • Fiona Powrie
    • Elizabeth H. Mann
    Reviews
    Nature
    Volume: 585, P: 509-517