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Showing 1–3 of 3 results
Advanced filters: Author: Alisa A. Mueller Clear advanced filters

  • This Review provides a comprehensive overview of fibroblast biology in rheumatoid arthritis and other chronic inflammatory diseases. The authors discuss insights into fibroblast behaviour and pathogenicity from single-cell and functional studies and describe how these findings have informed efforts to therapeutically target fibroblasts.

    • Angela E. Zou
    • Suppawat Kongthong
    • Michael B. Brenner
    Reviews
    Nature Reviews Rheumatology
    Volume: 21, P: 336-354

  • Satellite cells are crucial for growth and regeneration of skeletal muscle. Here the authors show that in response to muscle injury, macrophages secrete Adamts1, which induces satellite cell activation by modulating Notch1 signaling.

    • Hongqing Du
    • Chung-Hsuan Shih
    • Brian J. Feldman
    ResearchOpen Access
    Nature Communications
    Volume: 8, P: 1-11

  • Changes in intronic polyadenylation of the Pdgfra in fibro/adipogenic progenitors lead to increased expression of a shorter variant with a truncated kinase domain, which modulates pro-fibrotic pathways to reduce tissue fibrosis in muscle.

    • Alisa A. Mueller
    • Cindy T. van Velthoven
    • Thomas A. Rando
    Research
    Nature
    Volume: 540, P: 276-279