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Showing 1–3 of 3 results

Advanced filters: Author: Alisha Beirl Clear advanced filters

EMX2-GPR156-Gαi reverses hair cell orientation in mechanosensory epithelia

Sensory hair cells develop an asymmetric architecture to restrict stimulus detection to a single axis. Here the authors identify GPR156 as directing a 180-degree reversal in hair cell orientation through Gαi, downstream of EMX2 in the mouse inner ear and zebrafish lateral line.

Katie S. Kindt
Anil Akturk
Basile Tarchini
ResearchOpen Access17 May 2021
Nature Communications

Volume: 12, P: 1-19
Synaptically silent sensory hair cells in zebrafish are recruited after damage

Hair cells of the inner ear are mechanosensors that detect sound, and synapse onto afferent neurons. Here, the authors used calcium imaging to find that not all hair cells are synaptically engaged, but after damage these silent cells are synaptically engaged.

Qiuxiang Zhang
Suna Li
Katie S. Kindt
ResearchOpen Access11 Apr 2018
Nature Communications

Volume: 9, P: 1-16
Additive reductions in zebrafish PRPS1 activity result in a spectrum of deficiencies modeling several human PRPS1-associated diseases

Wuhong Pei
Lisha Xu
Shawn M. Burgess
ResearchOpen Access18 Jul 2016
Scientific Reports

Volume: 6, P: 1-17