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Showing 1–4 of 4 results
Advanced filters: Author: Allie C. Obermeyer Clear advanced filters

  • Rapid pH changes can trigger hollow vacuoles in associative condensates of pH-responsive biomolecules. Using a model enzyme–polymer system, how larger droplets and faster pH changes promote vacuole formation by creating unstable non-equilibrium compositions is shown. A physics-based model reproduces these observations, showing when and how vacuoles arise through spinodal decomposition.

    • Nisha Modi
    • Raghavendra Nimiwal
    • Allie C. Obermeyer
    ResearchOpen Access
    Nature Chemical Engineering
    Volume: 3, P: 47-56

  • Jane Liao and Allie C. Obermeyer explore the discovery, modification and applications of green fluorescent protein, best known for its use as a tool to cast light on cellular processes.

    • Jane Liao
    • Allie C. Obermeyer
    Comments & Opinion
    Nature Chemistry
    Volume: 15, P: 588

  • Here the authors design tripeptides that form dynamic soluble dispersions and undergo phase separation upon drying to assemble into porous particles. This evaporation-driven emulsification can be harnessed to encapsulate and stabilize biomolecules.

    • Dhwanit R. Dave
    • Salma Kassem
    • Rein V. Ulijn
    ResearchOpen Access
    Nature Materials
    Volume: 24, P: 1465-1475

  • Phase separation provides intracellular organisation via membraneless entities called biomolecular condensates. Here, the authors show that short, cationic peptide tags can drive biomolecular condensation of engineered proteins in E. coli through associative interactions with RNA.

    • Vivian Yeong
    • Jou-wen Wang
    • Allie C. Obermeyer
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-10