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Showing 1–3 of 3 results
Advanced filters: Author: Allison J. Bardin Clear advanced filters

  • It is unclear why certain tissues are more susceptible to the consequences of aneuploidy. Here, in Drosophila, Gogendeau et al.identify aneuploidy as the cause of lengthened G1 and premature differentiation in both neural and adult intestinal stem cells, which prevents cells with abnormal genomes from cycling.

    • Delphine Gogendeau
    • Katarzyna Siudeja
    • Renata Basto
    ResearchOpen Access
    Nature Communications
    Volume: 6, P: 1-15

  • The vascular system, plastic and positioned in the vicinity of tissues, is an undervalued regulator of adult stem cells. Two studies now show that the vascular-like Drosophila trachea is reshaped after intestinal damage or tumour formation and that this remodelling is required for compensatory intestinal stem cell proliferation and tumour growth.

    • Louis Gervais
    • Allison J. Bardin
    News & Views
    Nature Cell Biology
    Volume: 23, P: 580-582