Schmidt et al. develop and test a platform for the delivery of stereotactic radiotherapy to mouse models. The authors identify maximum tolerated doses for radiation delivered to the mouse lower abdomen and pelvis, and show that while ablative radiotherapy improves survival, it does not cure autochthonous prostate and colorectal tumor models.
- Daniel R. Schmidt
- Iva Monique T. Gramatikov
- Matthew G. Vander Heiden