Advanced search

Filter By:

Journal Check one or more journals to show results from those journals only.

Choose more journals

Article type Check one or more article types to show results from those article types only.
Subject Check one or more subjects to show results from those subjects only.
Date Choose a date option to show results from those dates only.

Custom date range

Clear all filters
Sort by:
Showing 1–2 of 2 results
Advanced filters: Author: Althea Hansel-Harris Clear advanced filters

  • Cryo-EM reveals how transthyretin moves, offering insights into ligand binding and amyloidogenesis. The work highlights the utility of cryo-EM in studying small proteins and uncovering targets for structure-based drug design in transthyretin amyloidosis.

    • Benjamin Basanta
    • Karina Nugroho
    • Gabriel C. Lander
    Research
    Nature Structural & Molecular Biology
    Volume: 32, P: 876-883

  • Covalent probes have emerged as a pivotal tool in drug discovery, presenting unique challenges for integrating structural data compared to non-covalent probes. Here, the authors explore the role of structure-based design in optimizing covalent probes, emphasizing computational methods to harness structural insights, potentially transforming drug design strategies across various fields.

    • Matthew Holcomb
    • Manuel Llanos
    • Stefano Forli
    ReviewsOpen Access
    Communications Chemistry
    Volume: 8, P: 1-12