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Showing 1–4 of 4 results
Advanced filters: Author: Alvin Pratama Clear advanced filters
  • Roquin is an RNA-binding protein that promotes the degradation of specific mRNAs and is crucial for the maintenance of peripheral immune tolerance. Here the authors show that, in addition to its target mRNAs, Roquin can bind miR-146a and the RISC component Ago2 to control homeostasis of both RNA species.

    • Monika Srivastava
    • Guowen Duan
    • Carola G. Vinuesa
    ResearchOpen Access
    Nature Communications
    Volume: 6, P: 1-13
  • Recent studies have highlighted the diversity and distinct nature of regulatory T cells in the intestine, where they must balance a multitude of signals from the microbiota and the diet to ensure immune homeostasis. But questions and controversies remain over their origins and regulation, as discussed here.

    • Deepshika Ramanan
    • Alvin Pratama
    • Christophe Benoist
    Reviews
    Nature Reviews Immunology
    Volume: 23, P: 749-762