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Showing 1–8 of 8 results

Advanced filters: Author: Alwin D. R. Huitema Clear advanced filters

Impact of age on exposure to oral antiandrogen therapies in clinical practice

Marie-Rose B. S. Crombag
Merel van Nuland
Jos H. Beijnen
Research02 Oct 2018
Prostate Cancer and Prostatic Diseases

Volume: 22, P: 168-175
Feasibility and efficacy of therapeutic drug monitoring of abiraterone in metastatic castration resistant prostate cancer patients

Maud B. A. van der Kleij
Marinda Meertens
Maud B. A. van der Kleij
ResearchOpen Access11 Feb 2025
British Journal of Cancer

Volume: 132, P: 635-642
Resistance to second-generation androgen receptor antagonists in prostate cancer

Survival of patients with metastatic prostate cancer has improved with the approval of second-generation androgen receptor antagonists. This Review discusses common genomic alterations leading to inevitable resistance to this therapy, and potential alternative therapeutic targets for treatment.

Keith T. Schmidt
Alwin D. R. Huitema
William D. Figg
Reviews19 Mar 2021
Nature Reviews Urology

Volume: 18, P: 209-226
Reasons for non-feasibility of therapeutic drug monitoring of oral targeted therapies in oncology – an analysis of the closed cohorts of a multicentre prospective study

Maud B. A. van der Kleij
Niels A. D. Guchelaar
Neeltje Steeghs
ResearchOpen Access06 Jul 2024
British Journal of Cancer

Volume: 131, P: 843-851
Peritoneal metastases from colorectal cancer belong to Consensus Molecular Subtype 4 and are sensitised to oxaliplatin by inhibiting reducing capacity

Jamila Laoukili
Alexander Constantinides
Onno Kranenburg
ResearchOpen Access22 Feb 2022
British Journal of Cancer

Volume: 126, P: 1824-1833
Phase 1 study of the pan-HER inhibitor dacomitinib plus the MEK1/2 inhibitor PD-0325901 in patients with KRAS-mutation-positive colorectal, non-small-cell lung and pancreatic cancer

Robin M. J. M. van Geel
Emilie M. J. van Brummelen
Jan H. M. Schellens
ResearchOpen Access09 Mar 2020
British Journal of Cancer

Volume: 122, P: 1166-1174
Investigating the influence of relevant pharmacogenetic variants on the pharmacokinetics and pharmacodynamics of orally administered docetaxel combined with ritonavir

Maarten van Eijk
Dick Pluim
Jos H. Beijnen
Research01 Mar 2021
The Pharmacogenomics Journal

Volume: 21, P: 336-345
IHC-based Ki67 as response biomarker to tamoxifen in breast cancer window trials enrolling premenopausal women

Stacey E. P. Joosten
Marius Wellenstein
Wilbert Zwart
ResearchOpen Access20 Oct 2021
npj Breast Cancer

Volume: 7, P: 1-8