Frontotemporal dementia (FTD) is a common early-onset dementia caused by heterozygous mutations in the progranulin gene (GRN). Gerrits et al. demonstrate blood–brain barrier dysfunction and a severely affected neurovasculature in FTD-GRN.
- Emma Gerrits
- Lucia A. A. Giannini
- Bart J. L. Eggen