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Showing 1–3 of 3 results
Advanced filters: Author: Alyssa Thomas DeCruz Clear advanced filters

  • Spin-enhanced lateral flow tests use nanodiamonds for the sensitive, robust detection of disease biomarkers. Here, authors report a clinical evaluation of a test for SARS-CoV-2 antigen, finding 95.1% sensitivity (Ct ≤ 30) and 100% specificity, with detection 2.0 days earlier than conventional tests.

    • Alyssa Thomas DeCruz
    • Benjamin S. Miller
    • Rachel A. McKendry
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-13

  • Wastewater surveillance for disease outbreaks currently requires lab testing which causes delays. Here, authors develop ultra-sensitive quantum sensors enabling 2-hour near-source pathogen detection from raw wastewater with high sensitivity and specificity, creating a portable “lab-in-a-suitcase” system.

    • Da Huang
    • Alyssa Thomas DeCruz
    • Rachel A. McKendry
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-11

  • The feasibility of large-scale testing with lateral flow tests has been demonstrated in the COVID-19 pandemic. This Review examines lessons learned from the COVID-19 pandemic to inform the design and bioengineering of next-generation lateral flow tests to strengthen future diagnostic resilience.

    • Jobie Budd
    • Benjamin S. Miller
    • Rachel A. McKendry
    Reviews
    Nature Reviews Bioengineering
    Volume: 1, P: 13-31